ORAL DELIVERY of testosterone

The main challenge with the oral delivery of Testosterone is the high first pass metabolism that degrades the molecule in the liver, limiting its bioavailability. Testosterone is also poorly water soluble and has proven to be extremely difficult to administer orally in a safe and efficacious manner.

Utilizing TesoRx's novel drug delivery technology, Testosterone Undecanoate (TU) is formulated as a coated capsule. Upon release of contents in the small intestine, neoliposomal TU complexes form spontaneously and are absorbed directly into the lymphatic system. From the lymph, TU is directly released into the blood stream, bypassing the liver, resulting in enhanced bioavailability of the drug.

We have utilized the neoliposomal delivery platform for other indications including chemotherapy.

Read more about TesoRx’s oral Testosterone products for Hypogonadism in men and Constitutional Delay in Growth and Puberty for boys.