TesoRx Provides Update on Clinical Development Program for Oral Testosterone Candidate TSX-049

(San Francisco, Calif.) November 26, 2019 - TesoRx LLC today announced the successful completion of the first part of a multiple formulation study in canines and the initiation of the second and final part of the study in collaboration with ASKA Pharmaceutical. Part one of the study showed TSX-049 to have the improved absorption curves and established serum testosterone levels of up to four times higher than TSX-011. Successful completion of the study would allow for human clinical trials to be initiated by Q2 2020 with potential U.S. Food and Drug Administration approval as soon as 2023.

“Many testosterone products come with significant lifestyle restrictions for patients like needing to cover their skin or not have physical contact to reduce the risk of testosterone transference to loved ones,” said Michael Oefelein, Chief Medical Officer of TesoRx. “Our success with TSX-049 in a preclinical model means we may be able to offer an oral, once-daily product with more convenience and safety for patients in the future.”

TSX-049 is a novel, oral formulation of Testosterone containing Testosterone Undecanoate that is designed to help restore normal Testosterone levels in males with hypogonadism. By leveraging TesoRx’s proprietary proliposomal delivery platform to deliver modified Testosterone, TSX-049 has the potential to offer greater safety and convenience compared to existing topical and injectable treatments.

About TesoRX Pharma LLC

TesoRx Pharma LLC is focused on rapidly developing and commercializing pharmaceutical products in rare and specialty markets with limited treatment options and high unmet needs. Its growing pipeline includes assets in urology, oncology and rare diseases that have been formulated with TesoRx’s proprietary proliposomal delivery technology. The company was founded in 2010 through a collaboration with Western University of Health Sciences that includes joint R&D efforts at the TesoRx Centre of Excellence in Pomona, California. For more information, visit tesorx.com.

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